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Phyto Methylate, 60 Vcaps

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Vegan, Non-GMO, Dairy-Free, Soy-Free, Excipient Free
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Phyto Methylate from Premier Research Labs delivers the most dynamic support in methyl group supplementation for human nutrition today. Phyto-Methylate is a rich source of biologically available methyl donors and cofactors important for advanced cellular functions such as DNA methylation, homocysteine synthesis and protein synthesis. Phyto Methylate directly delivers advanced methylation through the fully activated methyl donors of folate as 5-methyltetrahydrofolate, B12 as methylcobalamin, B6 as pyridoxal-5 phosphate and choline bitartrate.

Methylation is the biochemical process of the transfer of one carbon atom and three hydrogen atoms, CH3 – a methyl group, from one substance to another. Supporting healthy methylation is vital to promoting healthy genetic expression and cellular functions. When sufficient methyl groups are available, it has a positive effect regulating many biochemical reactions throughout the body including cardiovascular, neurological, reproductive and detoxification systems

It is suggested that 60% of the population suffers from a genetic mutation compromising the proper conversion of unmethylated Bs

It is suggested that 60% of the population suffers from a genetic mutation compromising the proper conversion of unmethylated vitamin Bs. Without proper methyl transfer for homocysteine modulation, the necessary formation of methyl donors involved in cardiovascular, neurological, reproductive and detoxification functions cannot be adequately produced.         

The 3 Super Stars: Folate (as 5-Methyltetrahydrofolate), B12 (as Methylcobalamin), B6 (as Pyridoxal-5-Phosphate)

Premier Research Labs’ Phyto-Methylate contains three fully active co-enzymes of the blood -circulating forms of folate (as 5-methytetrahydrofolate), vitamin B12 (as methylcobalamin) and B6 (as pyridoxal-5-phosphate). While the body is able to absorb food-source vitamin Bs, it must further convert them to these three coenzyme forms in order for it to become metabolically active in the body. Unfortunately, over half of the U.S. population is unable to metabolize the unmethylated forms of specific B vitamins, namely folate and vitamin B12.  When folate (as 5-methyltetrahydrofolate) and vitamin B12 (as methylcobalamin) are provided to the body in these active biologically forms, they are able to yield optimal bioavailability as well as tissue retention which can promote healthy methyl formation.

Choline Substantially Contributes to the Pool of Methyl Groups

Choline substan­tially contributes to the pool of methyl groups that can be used for one-carbon transfer reactions with DNA and protein. Choline is oxidized in a two-step process and subsequently remethylates homocysteine to S-adenosylmethionine, a meth­yl donor necessary for the synthesis of DNA and RNA, the myelin insulation for neurons and other biological materials.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant or nursing, please consult your healthcare professional before using this or any product. Keep out of the reach of children.

Additional Reading:

Why Premier Research Labs Products?


Phyto Mehtylate from Premier Research Labs contains the following:

  • Supplement facts: Serving Size 2 capsules, 30 servings
  • Choline 110 mg: (from grape fermentation as Choline Bitartrate)
  • Vitamin B6 25 mg: (including Pyrdoxal-5-Phosphate)
  • Vitamin B12 1,000 mcg: (Methylocbalamin)
  • Folate 680 mcg: (as 5-Methyltetrahydrofolate)
  • Green Methyl Support 558 mg: Organic Rice Concentrate (Oryza sativa), Organic Barley (leaf) (Hordeum vulgare),
    Organic Oat Grass (Avenea sativa)
  • Other Ingredients: Plant-Source Capsule (cellulose, water)

Recommended Use:

Take 2 capsules daily or as directed by a health professional.

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