Phyto Methylate from Premier Research Labs contains activated folate and activated B vitamins with choline for advanced methylation neurological and cardiovascular support.
Contains Barley, so not gluten-free.
Phyto-Methylate is a rich source of biologically available methyl donors and cofactors important for advanced cellular functions such as DNA methylation, homocysteine synthesis and protein synthesis. Phyto-Methylate directly delivers advanced methylation through the fully activated methyl donors of folate as 5-methyltetrahydrofolate, B12 as methylcobalamin, B6 as pyridoxal-5-phosphate and choline bitartrate.
Supporting healthy methylation is vital to promoting healthy genetic expression and cellular functions. When sufficient methyl groups are available, it has a positive effect regulating many biochemical reactions throughout the body including cardiovascular, neurological, reproductive and detoxification systems.
It is suggested that 60% of the population suffers from a genetic mutation compromising the proper conversion of unmethylated Bs
It is suggested that 60% of the population suffers from a genetic mutation compromising the proper conversion of unmethylated vitamin Bs. Without proper methyl transfer for homocysteine modulation, the necessary formation of methyl donors involved in cardiovascular, neurological, reproductive and detoxification functions cannot be adequately produced.
The 3 Super Stars: Folate (as 5-Methyltetrahydrofolate), B12 (as Methylcobalamin), B6 (as Pyridoxal-5-Phosphate)
Premier Research Labs’ Phyto-Methylate contains three fully active co-enzymes of the blood -circulating forms of folate (as 5-methytetrahydrofolate), vitamin B12 (as methylcobalamin) and B6 (as pyridoxal-5-phosphate). While the body is able to absorb food-source vitamin Bs, it must further convert them to these three coenzyme forms in order for it to become metabolically active in the body. Unfortunately, over half of the U.S. population is unable to metabolize the unmethylated forms of specific B vitamins, namely folate and vitamin B12. When folate (as 5-methyltetrahydrofolate) and vitamin B12 (as methylcobalamin) are provided to the body in these active biologically forms, they are able to yield optimal bioavailability as well as tissue retention which can promote healthy methyl formation.
Choline Substantially Contributes to the Pool of Methyl Groups
Choline substantially contributes to the pool of methyl groups that can be used for one-carbon transfer reactions with DNA and protein. Choline is oxidized in a two-step process and subsequently remethylates homocysteine to S-adenosylmethionine, a methyl donor necessary for the synthesis of DNA and RNA, the myelin insulation for neurons and other biological materials.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant or nursing, please consult your healthcare professional before using this or any product. Keep out of the reach of children.
Premier Research Labs Phyto Methylate contains the following:
2 Capsules Provides:
Choline (from grape fermentation as Choline Bitartrate) . . . . . . 110 mg
Vitamin B6 (including Pyrdoxal-5-Phosphate) . . . . . . . . . . . . . 25 mg
Vitamin B12 (Methylocbalamin) . . . . . . . . . . . . . . . . . . . . . . 1000 mcg
Folate (as 5-Methyltetrahydrofolate) . . . . . . . . . . . . . . . . . . . .400 mcg
Green Methyl Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558 mg
Organic Rice Concentrate (Oryza sativa), Organic Barley (leaf) (Hordeum vulgare),
Organic Oat Grass (Avenea sativa) Organic Parsley (leaf) (Petroselinum crispum)
Other Ingredients: Vegetable Capsules (hydroxypropyl methyl cellulose)
Recommended Use: Take 2 capsules daily or as directed by a health professional.
The manufacture date is the first six numbers of the lot number on the bottle, it is written year-month-day. The industry standard shelf life is 2 years from the manufacture date, but Premier nitrogen flushes the bottles to remove the oxygen, allowing the product to keep for 2 – 5 years. Oils and probiotics will lose potency faster than herbs or minerals.