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Methyl FMT, 60 caps

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Methyl FMT by NeuroScience: Fundamental methylation support and complete cofactor fuel designed for the entire family, from genetics and mood to healthy homocysteine.

Replaces Sanesco Methyl Max

The stress and methylation connection: 

  • Rapid rise and decline in cortisol after stress is considered the desirable dynamic, adaptive response. Conversely, changes in cortisol stress reactivity marks susceptibility for systemic complications and can be impacted by internal and external factors.
  • Exposure to stressors/trauma can impact DNA methylation that is functionally relevant for stress programming in the human brain.
  • Methylation is associated with balanced cortisol stress reactivity.

Combining Methyl FMT and Calm CP supports healthy cortisol at the genomic and cellular level for short- and long-term cortisol management.

Key Ingredients:

Riboflavin (B2):

  • Essential for MTHFR and MTRR coenzyme FAD in the folate cycle
  • Riboflavin supplementation has been shown to significantly reduce homocysteine levels in those with genetic predisposition

Niacin (B3):

  • Niacin, in the form of NAD, is a necessary cofactor for the enzymes DHFR in the folate/tetrahydrobiopterin cycles and S-adenosylhomocysteine hydrolase in the methionine cycle

Vitamin B6:

  • Essential cofactor for multiple enzymes in the methylation and transsulfuration pathways including SHMT, CBS, and CTH3,4
  • Essential cofactor for synthesis of neurotransmitters such as dopamine, GABA, norepinephrine, epinephrine, and serotonin

L-5-MTHF (B9):

  • Primary form of folate used by the body; does not require metabolism for absorption
  • Patented crystallization form for preferred stability

Vitamin B12:

  • Essential cofactor for the metabolism of L-5-MTHF in the folate pathway and homocysteine activity in the methionine pathway


  • Specific form of magnesium bound to glycine molecules naturally creating a low weight chelate with enhanced bioavailability
  • Required cofactor for methionine adenosyltransferase, the enzyme responsible for synthesizing SAMe in the methionine pathway


  • Essential cofactor enzymes in the methylation pathway including MTR and BHMT


  • Potent methyl donor and substrate for BHMT, sparing choline resources
  • Trimethylglycine supplementation has been shown to support healthy homocysteine levels

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant or nursing, please consult your healthcare professional before using this or any product. Keep out of the reach of children.

Order the Sanesco HPA Lab Test to identify which NeuroScience and Sanesco products will work best for you.

Additional Reading:

Methyl FMT by NeuroScience

Methyl FMT by NeuroScience contains the following:
Serving Size: 2 Capsules
Servings Per Container: 30

Per Serving:

  • Riboflavin (as riboflavin 5'-phosphate) 25mg
  • Niacin (as niacinamide) 8mg NE
  • Vitamin B6 (as pyridoxal 5'-phosphate) 10mg
  • Folate (L-5-methyltetrahydrofolate, calcium salt) 400mcg
  • Vitamin B12 (as methylcobalamin) 500mcg
  • Magnesium (as magnesium bisglycinate chelate) 25 mg
  • Zinc (as zinc bisglycinate chelate) 3mg
  • Trimethylglycine (as betaine anhydrous)

Other Ingredients: Vegetable capsule (hypromellose, water), silica, magnesium stearate (vegetable source)

Recommended Use: Take capsules based on the appropriate age group below or as directed by your healthcare provider. Do not exceed suggested use.

  • Ages 4-8 years: 1 capsule daily.
  • Ages 9-13 years: 1-2 capsules daily.
  • Ages >14 years: 2 capsules daily.